There are three standard bets you can make in any NFL game. The first standard NFL bet is the spread on a game. One of the teams will be favored usually in between a range of zero, or pick em, to a touchdown. The second standard NFL bet is the total. This is when the book sets a number to try and predict the combined final score and the bettor either bets under or over that number. The third and final standard NFL bet is the moneyline. This is the most simple. If you just want to bet on which team will win, regardless of the score or spread, go with the moneyline.